Towards FUS lung cancer ablation: the lung flooding process from a physiological and physical view point
نویسندگان
چکیده
Background/introduction Unilateral lung flooding replaces air with saline in lung parenchyma. It has been shown, that in flooded condition ultrasound guidance and HIFU ablation of central lung cancer tissue is feasible. The flooding process generates a saline-lung compound which is different than known parenchymal tissue. Complete understanding of the flooding process is essential for its implementation in a HIFU cancer ablation scheme. Therefore a detailed excurse of the flooding mechanism and its influences in acoustic and physiological conditions will be discussed. However, before initiating the first human pilot, several issues remain. So far the usability of MR guiding and aspects of HIFU effects on flooded lung parenchyma are unknown.
منابع مشابه
Feasibility of FUS lung cancer treatment using unilateral lung flooding
Background Lung is not considered for HIFU ablation so far. By replacing air with saline, therapeutic ultrasound could penetrate parenchyma and reach underlying cancer. Unilateral lung flooding is known for ultrasound guided thoracoscopic surgery. Lung cancer is prevalent in oncology and the most mortal cancer entity, its cure requires operability and results in loss of parenchyma. Whereby we w...
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